Science Minute Audiocast: The Power of Supercomputers
Jeremy Smith, Governor’s Chair for Molecular Biophysics, discusses how supercomputers can help find new drugs for diseases like cancer and diabetes.
Computer Simulations Identify Chemical Key to Diabetes Drug Alternatives
Jeremy Smith, Governor’s Chair for Molecular Biophysics, has discovered a chemical compound that could lower sugar levels as effectively as the diabetes drug metformin but with a lower dose.
Knoxville News Sentinel: UT Experts Believe Syria Events Call for More Research
The Syrian government’s use of chemical weapons in attacks on its own people is raising questions in the research community about the need to counteract such activity, according to two experts at the University of Tennessee. The Knoxville News Sentinel recently interviewed Jeremy Smith, a governor’s chair researcher at UT and Oak Ridge National Laboratory
News Sentinel Highlights Smith Research on Combating ‘Superbugs’
The Knoxville News Sentinel highlighted the research of Jeremy Smith, which involves the use of supercomputer simulations to help discover a new class of drug candidates that hold promise to combat antibiotic resistance. He is conducting the research with a team at Oak Ridge National Laboratory.
UT-ORNL Supercomputer Simulations Help Develop New Approach to Fight Antibiotic Resistance
A joint UT-Oak Ridge National Laboratory research project involving supercomputer simulations has played a key role in discovering a new class of drug candidates that hold promise to combat antibiotic resistance.
UT-ORNL Team Hopes to Ease Path from Vegetation to Biofuel
A UT-ORNL team led by Governor’s Chair Jeremy Smith is using supercomputing to figure out ways to ease the path of turning vegetation into biofuel.
Bio Fuels Digest, Others Highlight Lignin Research by UT-ORNL Faculty Member
Industry publications highlight Jeremy Smith’s lignin research.
Titan Supercomputer Probes Depths of Biofuel’s Biggest Barrier
Ask a biofuel researcher to name the single greatest technical barrier to cost-effective ethanol, and you’re likely to receive a one-word response: lignin. To better understand exactly how lignin persists, researchers ORNL created one of the largest biomolecular simulations to date using the Titan supercomputer to track and analyze millions of atoms. The research was
New Supercomputer Simulations Enhance Understanding of Protein Motion and Function
Supercomputing simulations led by a joint UT-Oak Ridge National Laboratory team could change how researchers understand the internal motions of proteins that play functional, structural and regulatory roles in all living organisms. The team’s results are featured in Nature Physics.
UT Researchers Use Computers for Drug Research
UT researchers are using supercomputing to simulate the interactions of drug compounds and proteins in the body. The computers allow them to rapidly collect and analyze data which could make medicine cheaper, find new uses for existing drugs, and enhance the understanding of a drug’s potential side effects.
Time: Squid Protein: Our Best Defense Against Chemical Weapons?
Time wrote about a recent study by UT and ORNL researchers, published in the Journal of Physical Chemistry, that focuses on the engineering of enzymes produced in the bodies of squid that may be effective in breaking down nerve gasses and other deadly chemical weapons. The team aspires to create a prophylactic drug from these
UT, ORNL Scientists’ Discoveries Could Help Neutralize Chemical Weapons
Researchers at UT are a step closer to creating a prophylactic drug that would neutralize the deadly effects of the chemical weapons used in Syria and elsewhere. Jeremy Smith, UT-ORNL Governor’s Chair and an expert in computational biology, is part of the team that is trying to engineer enzymes—called bioscavengers—so they work more efficiently against